BDBM475561 1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-::US10851083, Example 173::US11618744, Example 173

SMILES OC(=O)c1cnn(c1)-c1nc2cc(c(Cl)cc2[nH]1)S(=O)(=O)Cc1ccc(Cl)cc1

InChI Key InChIKey=YDKTXLMBLOTICX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475561   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475561(1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50:  15.8nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475561(1-[6-Chloro-5-(4-chloro-phenylmethanesulfonyl)-1H-...)
Affinity DataIC50:  15.8nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent