BDBM475573 1-(6-Chloro-9H-purin-8-yl)-1H-pyrazole-4-carboxylic::US10851083, Example 185::US11618744, Example 185

SMILES OC(=O)c1cnn(c1)-c1nc2c(Cl)ncnc2[nH]1

InChI Key InChIKey=MARXCUJJLZCPGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475573   

TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475573(1-(6-Chloro-9H-purin-8-yl)-1H-pyrazole-4-carboxyli...)
Affinity DataIC50:  5.01E+3nMAssay Description:The PHD2 181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEgl nine homolog 1 [181-417](Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM475573(1-(6-Chloro-9H-purin-8-yl)-1H-pyrazole-4-carboxyli...)
Affinity DataIC50:  5.01E+3nMAssay Description:The PHD2181-417 polypeptide (3 μg) was pre-incubated for 30 minutes with test compound prior to assessing the enzymatic activity of the polypept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent