BDBM475673 5-(2-(2-(1H-pyrazolo[4,3-b]pyridin- 1-yl)-7,8-dihydropyrido[4,3-d]pyrimidin- 6(5H)-yl)-1-hydroxyethyl)-4- methylisobenzofuran-1(3H)-one (Enantiomer-I)::US10851108, Example 41-I
SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCc2nc(ncc2C1)-n1ncc2ncccc12
InChI Key InChIKey=BCRHBHIDTOBOGG-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 475673
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb
US Patent
Bristol-Myers Squibb
US Patent
Affinity DataIC50: 23nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair