BDBM475674 1-(6-(2-hydroxy-2-(4-methyl-1-oxo- 1,3-dihydroisobenzofuran-5-yl)ethyl)- 5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin- 2-yl)-1H-pyrrolo[2,3-c]pyridine- 4-carbonitrile (Enantiomer-I)::US10851108, Example 42-I

SMILES Cc1c2COC(=O)c2ccc1C(O)CN1CCc2nc(ncc2C1)-n1ccc2c(cncc12)C#N

InChI Key InChIKey=PUJAQEPZWLZQKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475674   

TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM475674(1-(6-(2-hydroxy-2-(4-methyl-1-oxo- 1,3-dihydroisob...)
Affinity DataIC50:  34nMAssay Description:The coverslip plated with cells was placed in the experiment chamber perfused with bath solution composed of (in mM): 135 NaCl, 5 KCl, 2 CaCl2, 1 MgC...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent