BDBM475727 (E)-1-[(3aS,3bS,6aR,6bR)-5-((R)-4,5,6,7- tetrahydro-1H-benzotriazole-5-carbonyl)- octahydro-cyclobuta[1,2-c;3,4-c']dipyrrol- 2-yl]-3-(4-trifluoromethoxy-phenyl)- propenone::US10849881, Example 1.006

SMILES FC(F)(F)Oc1ccc(\C=C\C(=O)N2C[C@H]3[C@@H](C2)[C@@H]2CN(C[C@H]32)C(=O)[C@@H]2CCc3[nH]nnc3C2)cc1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475727   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475727((E)-1-[(3aS,3bS,6aR,6bR)-5-((R)-4,5,6,7- tetrahydr...)
Affinity DataIC50:  8nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent