BDBM475735 US10851110, Example 64B::US11466017, Example 64B

SMILES N[C@@H]1[C@@H](F)CCC11CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1Cl

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475735   

TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475735(US10851110, Example 64B | US11466017, Example 64B)
Affinity DataIC50:  221nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM475735(US10851110, Example 64B | US11466017, Example 64B)
Affinity DataIC50:  221nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent