BDBM475735 US10851110, Example 64B::US11466017, Example 64B
SMILES N[C@@H]1[C@@H](F)CCC11CCN(CC1)c1cnc2c(n[nH]c2n1)-c1cccc(Cl)c1Cl
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 475735
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 221nMAssay Description:Phosphatase activity of full length wild-type PTPN11(PTPN11-WT) or PTPN11-E76K mutant enzyme was measured using the fluorogenic 6,8-difluoro-4-methyl...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 11 [E76K](Homo sapiens (Human))
Board Of Regents, The University Of Texas System
US Patent
Board Of Regents, The University Of Texas System
US Patent
Affinity DataIC50: 221nMAssay Description:Recombinant full-length wild-type and E76K mutant human PTPN11 proteins were cloned, expressed (E. coli system), and isolated via a two-step purifica...More data for this Ligand-Target Pair