BDBM475751 US10849881, Example 1.025::[(3aS,3bS,6aR,6bR)-5-(1H-benzotriazole- 5-carbonyl)-octahydro-cyclobuta[1,2-c;3,4- c']dipyrrol-2-yl]-(4-cyclopropylmethoxy- naphthalen-2-yl)-methanone

SMILES O=C(N1C[C@H]2[C@@H](C1)[C@@H]1CN(C[C@H]21)C(=O)c1cc(OCC2CC2)c2ccccc2c1)c1ccc2[nH]nnc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475751   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475751(US10849881, Example 1.025 | [(3aS,3bS,6aR,6bR)-5-(...)
Affinity DataIC50:  8.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent