BDBM475812 (1H-benzotriazol-5-yl)- {(3aS,3bS,6aR,6bR)-5-[4-ethoxy-1-(2,2,2- trifluoro-ethyl)-1H-indole-6-carbonyl]- octahydro-cyclobuta[1,2-c;3,4-c']dipyrrol- 2-yl}-methanone::US10849881, Example 1.085

SMILES CCOc1cc(cc2n(CC(F)(F)F)ccc12)C(=O)N1C[C@H]2[C@@H]3CN(C[C@@H]3[C@H]2C1)C(=O)c1ccc2[nH]nnc2c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 475812   

TargetAtaxin-1(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM475812((1H-benzotriazol-5-yl)- {(3aS,3bS,6aR,6bR)-5-[4-et...)
Affinity DataIC50:  2.70nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent