BDBM475928 Preparation of (2S,6R,11R)-3-(cyclopropylmethyl)-8-(4-(2-(2-(2-methoxyethoxy)ethoxy)ethyl)piperazin-1-yl)-6,11-dimethyl-3,4,5,6-tetrahydro-2,6-methanobenzo[d]azocin-1(2H)-one ::US10865186, Compound 1

SMILES COCCOCCOCCN1CCN(CC1)c1ccc2C(=O)[C@@H]3[C@H](C)[C@@](C)(CCN3CC3CC3)c2c1

InChI Key InChIKey=LZCOSDXSQQIXQB-DETITRACSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475928   

TargetKappa-type opioid receptor(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM475928(Preparation of (2S,6R,11R)-3-(cyclopropylmethyl)-8...)
Affinity DataKi:  619nMAssay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetKappa-type opioid receptor(Homo sapiens (Human))
Nektar Therapeutics

US Patent
LigandPNGBDBM475928(Preparation of (2S,6R,11R)-3-(cyclopropylmethyl)-8...)
Affinity DataIC50:  2.68E+3nMAssay Description:The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent