BDBM476371 US10875851, Example 27::naphthalen-1-yl (3S)-3-{[4- (aminomethyl)-3- methoxybenzyl]carbamoyl}-4-(3- cyclohexyl-D-alanyl)piperazine-1- carboxylate

SMILES COc1cc(CNC(=O)[C@@H]2CN(CCN2C(=O)[C@H](N)CC2CCCCC2)C(=O)Oc2cccc3ccccc23)ccc1CN

InChI Key InChIKey=JFSWWMRHAXRTCU-WDYNHAJCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476371   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476371(US10875851, Example 27 | naphthalen-1-yl (3S)-3-{[...)
Affinity DataIC50:  15.6nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent