BDBM476391 2-chlorophenyl (3S)-4-[(2R)-2- [cyclohexyl(methyl)amino]-2-(1- methylpiperidin-4-yl)acetyl]-3- [(thiophen-2- ylmethyl)carbamoyl]piperazine-1- carboxylate::US10875851, Example 47

SMILES CN([C@H](C1CCN(C)CC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cccs1)C(=O)Oc1ccccc1Cl)C1CCCCC1

InChI Key InChIKey=OIGVUBFBXSWCRA-LMSSTIIKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476391   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476391(2-chlorophenyl (3S)-4-[(2R)-2- [cyclohexyl(methyl)...)
Affinity DataIC50:  29.8nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent