BDBM476396 2-chlorophenyl (3S)-4-{(2R)-2- (cyclohexylamino)-2-[1-(2,2,2- trifluoroethyl)piperidin-4-yl]acetyl}-3- [(thiophen-2- ylmethyl)carbamoyl]piperazine-1- carboxylate::US10875851, Example 52

SMILES FC(F)(F)CN1CCC(CC1)[C@@H](NC1CCCCC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cccs1)C(=O)Oc1ccccc1Cl

InChI Key InChIKey=BOYFTCTXJJZBFV-XTEPFMGCSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476396   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476396(2-chlorophenyl (3S)-4-{(2R)-2- (cyclohexylamino)-2...)
Affinity DataIC50:  23.4nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent