BDBM476437 (2S)-1-[N2-(2-benzyl-2- azaspiro[4.5]dec-8-yl)-N6,N6- dimethyl-D-lysyl]-4- (cyclopentylacetyl)-N-(thiophen-2- ylmethyl)piperazine-2-carboxamide::US10875851, Example 93

SMILES CN(C)CCCC[C@@H](NC1CCC2(CCN(Cc3ccccc3)C2)CC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cccs1)C(=O)CC1CCCC1

InChI Key InChIKey=PZJSOPBELHUEHX-RHOOGNOTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476437   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476437((2S)-1-[N2-(2-benzyl-2- azaspiro[4.5]dec-8-yl)-N6,...)
Affinity DataIC50:  23.5nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent