BDBM476481 (2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- (4,4-dimethyl-5-phenyl-4,5-dihydro- 1,3-oxazol-2-yl)-N-(thiophen-2- ylmethyl)piperazine-2-carboxamide::US10875851, Example 137::US10875851, Example 140

SMILES CC1(C)N=C(OC1c1ccccc1)N1CCN([C@@H](C1)C(=O)NCc1cccs1)C(=O)[C@@H](CC1CCCCC1)NC1CCCCC1

InChI Key InChIKey=UTABTEKQFBFYOL-ZYWOQNTESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476481   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476481((2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- (4,4-dimethy...)
Affinity DataIC50:  19nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476481((2S)-1-(N,3-dicyclohexyl-D-alanyl)-4- (4,4-dimethy...)
Affinity DataIC50:  23.2nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent