BDBM476503 (2S)-4-(4,4-dimethyl-5-phenyl-4,5- dihydro-1,3-oxazol-2-yl)-1-[N-(1- methylethyl)-6-piperidin-1-yl-D- norleucyl]-N-(thieno[3,2-c]pyridin-2- ylmethyl)piperazine-2-carboxamide::US10875851, Example 159

SMILES CC(C)N[C@H](CCCCN1CCCCC1)C(=O)N1CCN(C[C@H]1C(=O)NCc1cc2cnccc2s1)C1=NC(C)(C)C(O1)c1ccccc1

InChI Key InChIKey=VGTHTSFVLVBHFO-FYQPVZKXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476503   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476503((2S)-4-(4,4-dimethyl-5-phenyl-4,5- dihydro-1,3-oxa...)
Affinity DataIC50:  27.4nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent