BDBM476511 (2S)-4-[(4S,5S)-5-(3-bromophenyl)-4- methyl-4,5-dihydro-1,3-oxazol-2-yl]- N-(3-chlorobenzyl)-1-(6-piperidin-1- yl-D-norleucyl)piperazine-2- carboxamide::US10875851, Example 167

SMILES C[C@@H]1N=C(O[C@H]1c1cccc(Br)c1)N1CCN([C@@H](C1)C(=O)NCc1cccc(Cl)c1)C(=O)[C@H](N)CCCCN1CCCCC1

InChI Key InChIKey=ZQAMNKMYTWWUJJ-VQCLQPKNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476511   

TargetCoagulation factor XII(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM476511((2S)-4-[(4S,5S)-5-(3-bromophenyl)-4- methyl-4,5-di...)
Affinity DataIC50:  36.1nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIIa can be determined using a relevant purified serin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent