BDBM476565 N'-butyl-4- phenoxybenzohydrazide::US10870618, Compound 1c

SMILES CCCCNNC(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=FBBSREZIVYGITQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 476565   

TargetHistone deacetylase 3(Homo sapiens (Human))
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476565(N'-butyl-4- phenoxybenzohydrazide | US10870618, Co...)
Affinity DataIC50:  312nMAssay Description:Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476565(N'-butyl-4- phenoxybenzohydrazide | US10870618, Co...)
Affinity DataIC50:  1.69E+3nMAssay Description:Allosteric inhibition of HDAC3 in HEK293 cell lysates pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Musc Foundation For Research Development

US Patent
LigandPNGBDBM476565(N'-butyl-4- phenoxybenzohydrazide | US10870618, Co...)
Affinity DataIC50:  312nMAssay Description:Allosteric inhibition of C-terminal His-tagged recombinant human HDAC3 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminom...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed