BDBM476602 N'-butylcinnamohydrazide::US10870618, Compound 1i
SMILES CCCCNNC(=O)\C=C\c1ccccc1
InChI Key InChIKey=FKXZPVNTHKXRQT-MDZDMXLPSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 476602
Affinity DataIC50: 294nMAssay Description:Recombinant HDACs 1, 2, and 3 (BPS Biosciences) were diluted to a concentration of 1 nM in HDAC buffer. 10 uL of this solution was added in 96-well f...More data for this Ligand-Target Pair
Affinity DataIC50: 1.44E+3nMAssay Description:Allosteric inhibition of HDAC3 in HEK293 cell lysates pre-incubated for 2 hrs before acetylated lysine-aminomethyl coumarin-BOC addition and measured...More data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Allosteric inhibition of C-terminal His-tagged recombinant human HDAC3 expressed in Sf9 cells pre-incubated for 2 hrs before acetylated lysine-aminom...More data for this Ligand-Target Pair