BDBM476663 US10870625, Compound 29

SMILES CCc1nc(N)nc(N)c1C#CC(SC)c1cc(ccc1OC)-c1ccc(cc1)C(O)=O

InChI Key InChIKey=PGSSQPCZSOJHPV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476663   

TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Connecticut

US Patent
LigandPNGBDBM476663(US10870625, Compound 29)
Affinity DataIC50:  1.96E+3nMAssay Description:Enzyme activity and inhibition assays were performed by monitoring the NADPH-dependent reduction of dihydrofolate catalyzed by the DHFR enzyme. The r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent