BDBM476668 US10870625, Compound 56

SMILES CCc1nc(N)nc(N)c1C#CCc1cc(ccc1OC)-c1cncn1C

InChI Key InChIKey=ZRBMCVGYUITEKK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476668   

TargetDihydrofolate reductase(Homo sapiens (Human))
University Of Connecticut

US Patent
LigandPNGBDBM476668(US10870625, Compound 56)
Affinity DataIC50:  1.45E+3nMAssay Description:Enzyme activity and inhibition assays were performed by monitoring the NADPH-dependent reduction of dihydrofolate catalyzed by the DHFR enzyme. The r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent