BDBM476677 (S)-8-(2-Imino-1,4-dimethyl-6- oxohexahydropyrimidin-4-yl) dibenzo[b,d]thiophene-2-carbonitrile::US10870635, Example 85

SMILES CN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#N

InChI Key InChIKey=VGOAETJNCUTHJV-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476677   

TargetBeta-secretase 1(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476677((S)-8-(2-Imino-1,4-dimethyl-6- oxohexahydropyrimid...)
Affinity DataIC50: >300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent