BDBM476686 (R)-6-Cyclopropyl-2-imino-3-methyl- 6-(8-(prop-1-yn-1-yl)dibenzo[b,d] thiophen-2-yl)tetrahydropyrimidin- 4(1H)-one::US10870635, Example 99

SMILES CC#Cc1ccc2sc3ccc(cc3c2c1)[C@@]1(CC(=O)N(C)C(=N)N1)C1CC1

InChI Key InChIKey=UDJZDQVQVXPDRT-HSZRJFAPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476686   

TargetBeta-secretase 1(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476686((R)-6-Cyclopropyl-2-imino-3-methyl- 6-(8-(prop-1-y...)
Affinity DataIC50: >300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent