BDBM476691 (S)-2-Imino-3-(2-methoxyethyl)-6- methyl-6-(8-(prop-1-yn-1-yl)dibenzo[b,d] thiophen-2-yl)tetrahydropyrimidin- 4(1H)-one::US10870635, Example 106

SMILES COCCN1C(=N)N[C@@](C)(CC1=O)c1ccc2sc3ccc(cc3c2c1)C#CC

InChI Key InChIKey=MRVOXMFCXREREJ-QHCPKHFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 476691   

TargetBeta-secretase 1(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476691((S)-2-Imino-3-(2-methoxyethyl)-6- methyl-6-(8-(pro...)
Affinity DataIC50: >300nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent