BDBM477249 US10889546, Example 57

SMILES OC(=O)CNC(=O)c1ncc(cc1O)C#CCOc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WKSCDDRDKBQPHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477249   

TargetEgl nine homolog 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM477249(US10889546, Example 57)
Affinity DataIC50:  825nMAssay Description:Inhibition of FITC-HIF1alpha (556 to 574 residues) binding to PHD2 (181 to 426 residues) (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEgl nine homolog 1(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM477249(US10889546, Example 57)
Affinity DataIC50:  540nMAssay Description:The EGLN-1 (or EGLN-3) enzyme activity is determined using mass spectrometry (matrix-assisted laser desorption ionization, time-of-flight MS, MALD...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent