BDBM477444 N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(5-oxo-4,5-dihydro-::US10889555, Example 222A::US10889555, Example 226B

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2c1OCC[C@]2(C)O)c1n[nH]c(=O)o1)c1c(F)ccc(Br)c1C

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477444   

TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477444(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  70nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477444(N-((1S,2R)-2-(3-bromo-6-fluoro-2-methylphenyl)-1-(...)
Affinity DataIC50:  80nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent