BDBM477564 4-cyano-N-(1S,2R)-(6-fluoro-2,3-dimethylphenyl)-1-(5-oxo-4,5- dihydro-1,3,4-oxadiazol-2-yl)propyl)-2-methoxybenzenesulfonamide::US10889555, Example 342::US11634395, Example 342

SMILES COc1cc(ccc1S(=O)(=O)N[C@@H]([C@H](C)c1c(F)ccc(C)c1C)c1n[nH]c(=O)o1)C#N

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477564   

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477564(4-cyano-N-(1S,2R)-(6-fluoro-2,3-dimethylphenyl)-1-...)
Affinity DataIC50:  90nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477564(4-cyano-N-(1S,2R)-(6-fluoro-2,3-dimethylphenyl)-1-...)
Affinity DataIC50:  90nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent