BDBM477648 4-(1-(5-(Ethoxymethyl)-4-(6-methoxypyridin-3-yl)-4H-1,2,4-triazol-3-yl)azetidin-3-yl)-7-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazine 31::US10889569, Example 31

SMILES CCOCc1nnc(N2CC(C2)N2CCOc3cc(F)ccc23)n1-c1ccc(OC)nc1

InChI Key InChIKey=CJJLZZQQTALGHL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 477648   

TargetVasopressin V1a receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477648(4-(1-(5-(Ethoxymethyl)-4-(6-methoxypyridin-3-yl)-4...)
Affinity DataIC50:  3.50E+3nMAssay Description:V1aR: The inhibition effect of the compounds of the present invention on the activity of human V1 aR protein expressed in HEK293/human V1aR stably tr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V2 receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477648(4-(1-(5-(Ethoxymethyl)-4-(6-methoxypyridin-3-yl)-4...)
Affinity DataIC50:  5.80E+3nMAssay Description:V2R: The inhibition effect of the compounds of the present invention on the activity of human V2R protein expressed in HEK293/human V2R cells was det...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVasopressin V1b receptor(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM477648(4-(1-(5-(Ethoxymethyl)-4-(6-methoxypyridin-3-yl)-4...)
Affinity DataIC50:  5.45E+4nMAssay Description:V1bR: The inhibition effect of the compounds of the present invention on the activity of human V1bR protein expressed in HEK293/human V1bR cells was ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent