BDBM478022 US10889592, Compound I-2::US11325917, Compound I-2

SMILES Cc1cnc2c(N)c(sc2n1)C(=O)NCCc1ccc(N2CCNCC2)c(Cl)c1

InChI Key InChIKey=RKBMPPDXAAJYSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478022   

TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Valo Health

US Patent
LigandPNGBDBM478022(US10889592, Compound I-2 | US11325917, Compound I-...)
Affinity DataIC50:  1.10E+3nMAssay Description:Ubiquitin-Rhodamine 110 Assay for USP28 Activity: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Valo Health

US Patent
LigandPNGBDBM478022(US10889592, Compound I-2 | US11325917, Compound I-...)
Affinity DataIC50:  1.10E+3nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent