BDBM478034 US10889592, Compound I-14

SMILES C[C@H](CNC(=O)c1sc2nc(C)cnc2c1N)c1cc(F)c(cc1F)N1C2CCC1CNC2

InChI Key InChIKey=VDBWJHBJMHKNMO-LMWSTFAQSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478034   

TargetUbiquitin carboxyl-terminal hydrolase 28(Homo sapiens)
Valo Early Discovery

US Patent
LigandPNGBDBM478034(US10889592, Compound I-14)
Affinity DataIC50:  6.00E+3nMAssay Description:USP28: Each assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Cor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent