BDBM478095 1-((3-(2-Chloro-8-cyanoindolizin-5-yl)pyridin-4-yl)thio)cyclobutane-1-carboxylic acid ::US10894038, Example 13

SMILES OC(=O)C1(CCC1)Sc1ccncc1-c1ccc(C#N)c2cc(Cl)cn12

InChI Key InChIKey=KQSUOXGUIVBJDS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478095   

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical

US Patent
LigandPNGBDBM478095(1-((3-(2-Chloro-8-cyanoindolizin-5-yl)pyridin-4-yl...)
Affinity DataIC50:  26nMAssay Description:HEK293-URAT1 cell Lines were donated by Japan Fuji Biomedical Research Institute. Negative control cell of HEK293 (MOCK cells) which was transfected ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent