BDBM478119 (R)-((6-(6-methoxy-1H-pyrrolo [2,3-b]pyridin-4-yl)-4-(3- methylmorpholino)pyridin-2- yl)imino)dimethyl-lambda6-sulfanone::US10894052, Example 14

SMILES COc1cc(-c2cc(cc(N=S(C)(C)=O)n2)N2CCOC[C@H]2C)c2cc[nH]c2n1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478119   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM478119((R)-((6-(6-methoxy-1H-pyrrolo [2,3-b]pyridin-4-yl)...)
Affinity DataIC50:  48nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent