BDBM478135 US10894052, Example 29::diethyl({6-[(3R)-3-methylmorpholin- 4-yl]-2-{1H-pyrrolo[2,3-b]pyridin-4- yl}pyrimidin-4-yl}imino)-lambda6- sulfanone

SMILES CCS(=O)(CC)=Nc1cc(cc(n1)-c1ccnc2[nH]ccc12)N1CCOC[C@H]1C

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478135   

TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM478135(US10894052, Example 29 | diethyl({6-[(3R)-3-methyl...)
Affinity DataIC50:  2nMAssay Description:Human full-length FLAG-TEV-ATR and His6-ATRIP were co-expressed in HEK293 cells. The cell pellet (20 g) was harvested and lysed in 100 mL of lysis bu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent