BDBM478489 N-(4'-(1 ((5-cyclopropyl-1H-pyrazol-3-yl)amino)-1-oxopropan-2-yl)-2,3,4,5- tetrahydro-[1,1'-biphenyl]-4-yl)acrylamide::US10894786, Comp. No 8
SMILES CC(C(=O)Nc1cc([nH]n1)C1CC1)c1ccc(cc1)C1=CCC(CC1)NC(=O)C=C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 478489
Affinity DataKd: 63nMAssay Description:Kinase-tagged T7 phage strains were grown in parallel in 24-well blocks in an E. coli host derived from the BL21 strain. E. coli were grown to log-ph...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair