BDBM47871 4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]carbonyl-1H-quinolin-2-one::4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]-1H-quinolin-2-one::4-[4-[3-(trifluoromethyl)phenyl]piperazine-1-carbonyl]carbostyril::4-[oxo-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]methyl]-1H-quinolin-2-one::CVD-0013258::ERI-UCB-a0b0dbcb-4::MLS000760808::SMR000370919::cid_2449860

SMILES FC(F)(F)c1cccc(c1)N1CCN(CC1)C(=O)c1cc(=O)[nH]c2ccccc12

InChI Key InChIKey=NKHDYQSOEVSMNT-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 47871   

Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47871(4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]car...)
Affinity DataIC50:  5.10E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM47871(4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]car...)
Affinity DataIC50:  3.80E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM47871(4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]car...)
Affinity DataIC50:  3.80E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Cornell University

LigandPNGBDBM47871(4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]car...)
Affinity DataIC50:  5.65E+3nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)