BDBM478735 1-(4-{(1R or 1S)-1-[2-({7-chloro-6-[1-(cyclopropylmethyl)-1H-pyrazol-4-yl]-1H-benzimidazol-2-yl}amino)pyridin-4-yl]ethyl}piperazin-1-yl)-3,3,3-trifluoropropan-1-one::US10894784, Example 122.02

SMILES CC(N1CCN(CC1)C(=O)CC(F)(F)F)c1ccnc(Nc2nc3ccc(-c4cnn(CC5CC5)c4)c(Cl)c3[nH]2)c1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478735   

TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM478735(1-(4-{(1R or 1S)-1-[2-({7-chloro-6-[1-(cyclopropyl...)
Affinity DataIC50:  1.20nMAssay Description:Recombinant full-length N-terminally His-tagged human TBK1, expressed in insect cells and purified by Ni-NTA affinity chromatography, was purchased f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent