BDBM47874 2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-4-carboxamide::CVD-0002707::MAT-POS-916a2c5a-2::MLS000760597::N-[2-(2-methoxyphenoxy)ethyl]-2-oxidanylidene-1H-quinoline-4-carboxamide::N-[2-(2-methoxyphenoxy)ethyl]-2-oxo-1H-quinoline-4-carboxamide::SMR000369854::cid_2558401

SMILES COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

InChI Key InChIKey=IOKPKVSTRDCKNE-UHFFFAOYSA-N

Data  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 47874   

Target3C-like protease(Avian infectious bronchitis virus)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  3.60E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  3.46E+3nMAssay Description:The assay was performed according to the published procedure. Briefly, compounds were seeded into assay-ready plates (Greiner 384PP, cat# 781280) usi...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  7.87E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat. no. 784900) using an Echo 555 acoustic dispenser, and dimethyl sulfoxide ...More data for this Ligand-Target Pair
TargetSerine protease 1(Homo sapiens (Human))
Israel Institution Of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  9.90E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetReplicase polyprotein 1ab(2019-nCoV)
Israel Institution Of Biological Research

LigandPNGBDBM47874(2-keto-N-[2-(2-methoxyphenoxy)ethyl]-1H-quinoline-...)
Affinity DataIC50:  7.23E+3nMAssay Description:Compounds were seeded into assay-ready plates (Greiner 384 low volume, cat 784900) using an Echo 555 acoustic dispenser, and DMSO was back-filled for...More data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)