BDBM478973 (R)-N-(4-(3-((4-cyclopropoxy-5- fluoropyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US10894788, Example 13::US11390618, Example 13

SMILES CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(F)c(OC2CC2)n1

InChI Key InChIKey=JSPKCIIHNUYIFM-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478973   

TargetCyclin-K/Cyclin-dependent kinase 12(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM478973((R)-N-(4-(3-((4-cyclopropoxy-5- fluoropyrimidin-2-...)
Affinity DataIC50:  5.50E+3nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 12(Homo sapiens)
Kinnate Biopharma

US Patent
LigandPNGBDBM478973((R)-N-(4-(3-((4-cyclopropoxy-5- fluoropyrimidin-2-...)
Affinity DataIC50:  5.50E+3nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent