BDBM478978 (R)-N-(4-(3-((5-chloro-4-(2,2,2- trifluoroethoxy)pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)propionamide::US10894788, Example 18

SMILES CCC(=O)Nc1ccc(cc1)C(=O)N1CC[C@H](C1)Nc1ncc(Cl)c(OCC(F)(F)F)n1

InChI Key InChIKey=SDAQVTLJJMJVCY-CQSZACIVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 478978   

TargetCyclin-dependent kinase 12(Homo sapiens)
Kinnate Biopharma

US Patent
LigandPNGBDBM478978((R)-N-(4-(3-((5-chloro-4-(2,2,2- trifluoroethoxy)p...)
Affinity DataIC50:  550nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent