BDBM478996 (R)-N-(4-(3-((4- morpholinopyrimidin-2- yl)amino)piperidine-1- carbonyl)phenyl)acrylamide::US10894788, Example 36::US11390618, Example 36

SMILES C=CC(=O)Nc1ccc(cc1)C(=O)N1CCC[C@H](C1)Nc1nccc(n1)N1CCOCC1

InChI Key InChIKey=RDFMFNHIFPYIBQ-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478996   

TargetCyclin-K/Cyclin-dependent kinase 12(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM478996((R)-N-(4-(3-((4- morpholinopyrimidin-2- yl)amino)p...)
Affinity DataIC50:  6.50E+4nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 12(Homo sapiens)
Kinnate Biopharma

US Patent
LigandPNGBDBM478996((R)-N-(4-(3-((4- morpholinopyrimidin-2- yl)amino)p...)
Affinity DataIC50:  5.01E+4nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent