BDBM479006 (R)-N-(4-(3-((4-((1-methyl-1H- pyrazol-4-yl)oxy)pyrimidin-2- yl)amino)pyrrolidine-1- carbonyl)phenyl)acrylamide::US10894788, Example 46::US11390618, Example 46

SMILES Cn1cc(Oc2ccnc(N[C@@H]3CCN(C3)C(=O)c3ccc(NC(=O)C=C)cc3)n2)cn1

InChI Key InChIKey=DBPKFNVENVWLCB-QGZVFWFLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479006   

TargetCyclin-K/Cyclin-dependent kinase 12(Homo sapiens (Human))
Kinnate Biopharma

US Patent
LigandPNGBDBM479006((R)-N-(4-(3-((4-((1-methyl-1H- pyrazol-4-yl)oxy)py...)
Affinity DataIC50:  5.50E+3nMAssay Description:The IC50 profile of compounds was determined using one protein kinase in a customized, thiol free assay. IC50 values were measured by testing 10 conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 12(Homo sapiens)
Kinnate Biopharma

US Patent
LigandPNGBDBM479006((R)-N-(4-(3-((4-((1-methyl-1H- pyrazol-4-yl)oxy)py...)
Affinity DataIC50:  5.50E+3nMAssay Description:For the assays, 5 μl solution from each well of the compound dilution plates/10% DMSO were transferred into the assay plates. The final volume o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent