BDBM479509 3-amino-N-(2,6-difluorobenzyl)-5- (4-fluorophenyl)-6-(1-methyl-6- oxo-1,6-dihydropyridin-3-yl) pyrazine-2-carboxamide::US10898481, Compound 29::US11571420, Compound 29

SMILES Cn1cc(ccc1=O)-c1nc(C(=O)NCc2c(F)cccc2F)c(N)nc1-c1ccc(F)cc1

InChI Key InChIKey=WMTYEJRWAPGQDY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479509   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479509(3-amino-N-(2,6-difluorobenzyl)-5- (4-fluorophenyl)...)
Affinity DataIC50:  2.30nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479509(3-amino-N-(2,6-difluorobenzyl)-5- (4-fluorophenyl)...)
Affinity DataIC50:  2.30nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent