BDBM479510 6-([1,2,4]triazolo[4,3-a]pyridin-6-yl)-3- amino-N-(2,6-difluorobenzyl)-5- (oxazol-2-yl)pyrazine- 2-carboxamide::US10898481, Compound 34::US11571420, Compound 34

SMILES Nc1nc(-c2ncco2)c(nc1C(=O)NCc1c(F)cccc1F)-c1ccc2nncn2c1

InChI Key InChIKey=BEFFDNOKNRRUKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 479510   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479510(6-([1,2,4]triazolo[4,3-a]pyridin-6-yl)-3- amino-N-...)
Affinity DataIC50:  3.70nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479510(6-([1,2,4]triazolo[4,3-a]pyridin-6-yl)-3- amino-N-...)
Affinity DataIC50:  3.70nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent