BDBM479530 (R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-(oxazol-2-yl)-N- ((tetrahydrofuran-2-yl)methyl)pyrazine- 2-carboxamide::US10898481, Compound 126::US11571420, Compound 126

SMILES Cc1cnc2ccc(cn12)-c1nc(C(=O)NC[C@H]2CCCO2)c(N)nc1-c1ncco1

InChI Key InChIKey=ZMNJVFVXFGTUGF-CQSZACIVSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 479530   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479530((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50:  1.40nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479530((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50:  78nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479530((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50:  1.40nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
Dizal (Jiangsu) Pharmaceutical

US Patent
LigandPNGBDBM479530((R)-3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl...)
Affinity DataIC50:  78nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent