BDBM479533 3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-(oxazol-2-yl)-N-(oxetan-2- ylmethyl)pyrazine-2-carboxamide (isomer 1)::US10898481, Compound 134::US10898481, Compound 135::US11571420, Compound 135

SMILES Cc1cnc2ccc(cn12)-c1nc(C(=O)NCC2CCO2)c(N)nc1-c1ncco1

InChI Key InChIKey=KRMSXKRAKMCMKK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 479533   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  5.5nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  216nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  2nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  161nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  5.5nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  216nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  2nMAssay Description:Binding affinity and specificalities of the compounds against different subtype of human adenosine receptors (hA1, hA2a, hA2b, and hA3) were characte...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM479533(3-amino-6-(3-methylimidazo[1,2-a] pyridin-6-yl)-5-...)
Affinity DataIC50:  161nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent