BDBM480004 (R)-1-(3-(1-(4-(2-fluoro-3-methoxyphenoxy)phenyl)imidazo[1,5-a]pyrazin-3-yl)piperidin-1-yl)prop-2-en-1-one::US10933063, Compound 1::US11554118, Compound 1
SMILES COc1cccc(Oc2ccc(cc2)-c2nc([C@@H]3CCCN(C3)C(=O)C=C)n3ccncc23)c1F
InChI Key InChIKey=UULCMWFOJYIYAC-LJQANCHMSA-N
Data 14 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 14 hits for monomerid = 480004
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 30nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: <10nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 550nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: >1.00E+5nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 550nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:The following Table shows the activity of selected compounds of this invention in the BTK, TEC, BLK, LYN, LCK inhibition assay. More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: <10nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: <10nMAssay Description:Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were performed in a reaction volume...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 550nMAssay Description:The following Table shows the activity of selected compounds of this invention in the BTK, TEC, BLK, LYN, LCK inhibition assay. More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The following Table shows the activity of selected compounds of this invention in the BTK, TEC, BLK, LYN, LCK inhibition assay. More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:The following Table shows the activity of selected compounds of this invention in the BTK, TEC, BLK, LYN, LCK inhibition assay. More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 550nMAssay Description:The following Table shows the activity of selected compounds of this invention in the BTK, TEC, BLK, LYN, LCK inhibition assay. More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Suzhou Baijibugong Pharmaceutical Technology
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:Btk and Other Kinases: Btk kinase activity was determined using a homogenous time resolved fluorescence (HTRF) methodology. Measurements were perform...More data for this Ligand-Target Pair