BDBM480412 (R)-3-(tert-butyl)-N-(8-(4-((1-methyl-1H-pyrazol-3-yl)amino)-1,3,5-triazin-2-yl)-2-(oxetan-3-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-5-yl)-1,2,4-oxadiazole-5-carboxamide ::US10899753, Example 98

SMILES Cn1ccc(Nc2ncnc(n2)-c2ccc3[C@@H](CCN(Cc3c2)C2COC2)NC(=O)c2nc(no2)C(C)(C)C)n1

InChI Key InChIKey=JWLQWNGDMGXYPG-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480412   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM480412((R)-3-(tert-butyl)-N-(8-(4-((1-methyl-1H-pyrazol-3...)
Affinity DataIC50: <1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent