BDBM480451 5-(tert-butyl)-N-(2-methyl-4-(4-((1-methyl-1H-pyrazol-4-yl)amino)-1,3,5-triazin-2-yl)benzyl)-1,3,4-oxadiazole-2-carboxamide ::US10899753, Example 110

SMILES Cc1cc(ccc1CNC(=O)c1nnc(o1)C(C)(C)C)-c1ncnc(Nc2cnn(C)c2)n1

InChI Key InChIKey=JKHCSZDJNMILSJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 480451   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Biogen Ma

US Patent
LigandPNGBDBM480451(5-(tert-butyl)-N-(2-methyl-4-(4-((1-methyl-1H-pyra...)
Affinity DataIC50:  5.5nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent