BDBM480916 8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrazin-2-yl)cyclobutyl]amino}pyrimidin-5-yl)methanone::US10906888, Example 130::US10906888, Example 157

SMILES O=C(N1CCC2(C1)CCOCC2)c1cnc(NC2(CC2)c2cnccn2)nc1

InChI Key InChIKey=UPRUVVBRLBNFMW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480916   

TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM480916(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrazin-2-yl)...)
Affinity DataIC50:  0.875nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM480916(8-oxa-2-azaspiro[4.5]dec-2-yl(2-{[1-(pyrazin-2-yl)...)
Affinity DataIC50: <0.0410nMAssay Description:The test inhibitors were solubilized in DMSO to a stock concentration of 30 mM. On the day of the assay, dose response plates were prepared by diluti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent