BDBM481590 4-(2-(2-((2,2'-dichloro-3'-(1- methyl-5-(1- sulfamoylpiperidin-4-yl)- 4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)-[1,1'- biphenyl]-3-yl)carbamoyl)- 1-methyl-1,4,6,7-tetrahydro- 5H-imidazo[4,5-c]pyridin- 5- yl)ethyl)bicyclo[2.2.1] heptane-1-carboxylic acid::US10906920, Example 8

SMILES Cn1c2CCN(CCC34CCC(CC3)(C4)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)S(N)(=O)=O)c1Cl

InChI Key InChIKey=BCWAYDRRYIHFTC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481590   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM481590(4-(2-(2-((2,2'-dichloro-3'-(1- methyl-5-(1- sulfam...)
Affinity DataIC50: <5nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent