BDBM481772 (R)-3-(2-(4-chlorophenyl)- 2-fluoroethyl)-5-((7-methyl- 6-oxo-6H-purin-1(7H)- yl)methyl)-1,3,4-oxadiazol- 2(3H)-one::US10913742, Example 14
SMILES Cn1cnc2ncn(Cc3nn(C[C@H](F)c4ccc(Cl)cc4)c(=O)o3)c(=O)c12
InChI Key InChIKey=RSSHXKVUURRAKX-LBPRGKRZSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 481772
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 34nMAssay Description:The IC50 (effective concentration) of compounds on the human and rat TRPA1 channels were determined using a FLIPR Tetra instrument. CHO cells express...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Rattus norvegicus)
Genentech
Curated by ChEMBL
Genentech
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Antagonist activity at rat TRPA1More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human TRPA1 expressed in CHO cells measured by calcium based FLIPR assayMore data for this Ligand-Target Pair